11.beta.-phenyl-gonanes, their manufacture and...

C - Chemistry – Metallurgy – 07 – J

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C07J 1/00 (2006.01) C07D 319/06 (2006.01) C07J 9/00 (2006.01) C07J 15/00 (2006.01) C07J 21/00 (2006.01) C07J 41/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1310630

ABSTRACT OF THE DISCLOSURE 13-alkyl-11.beta.-phenyl-gorlanes of general formula 1 (I) Image where A and B together stand for an oxygen atom, a CH2 group or a second bond between carbon atoms 9 and 10, X stands for an oxygen atom or the hydroxyimino grouping N?OH, R1 stands for a straight-chained or branched, saturated or unsaturated alkyl radical with up to 8 carbon atoms, which is to contain the grouping ? with X in the aforementioned meaning, R2 stands for a methyl or ethyl radical in the ? or .beta. position, R9, R10, R11 and R12 each stand for a hydrogen atom, a hydroxy, alkyl, alkoxy or acyloxy group with 1 to 4 carbon atoms respectively or a halogen atom and R3 and R4 have different meanings which have antigestagenic and antigulcocorticoid effects.

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