C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
167/191, 260/40,
C07J 1/00 (2006.01) A61K 31/565 (2006.01) C07J 11/00 (2006.01) C07J 21/00 (2006.01) C07J 33/00 (2006.01)
Patent
CA 1314869
ABSTRACT The present invention is concerned with novel 11-methylene- oestr-15-enes of the formula: Image (formula I) wherein R1 = H or acyl with 1-18 C-atoms, preferably H, R2 = ethinyl, vinyl, chloroethinyl, allyl or propinyl; ethinyl being preferred, and R3 = O or H2, preferably O. further the present invention is concerned with processes for the preparation of the above compounds and with pharmaceutical compositions comprising these compounds. The compounds possess powerful gestagenic properties and only slight androgenic side- effects.
513454
Akzo N.v.
Fetherstonhaugh & Co.
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