C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/209, 260/238
C07D 498/04 (2006.01) A61K 31/55 (2006.01) C07D 207/333 (2006.01) C07D 401/06 (2006.01)
Patent
CA 1267893
Abstract 11-Substituted 5H,11H-pyrrolo(2,1-c][1,4]benzoxazepine, a process for their preparation and their use as medicaments There are described novel 11-substituted 5H,11H- pyrrolo[2,1-c][1,4]benzoxazepines of the general formula Image (I) where m and n are each independently 0, 1 or 2 and m+n is 1 or 2, X and Y are each indepdently hydrogen, loweralkyl or halogen, and R is hydrogen, cyano, -C(NH2)NOH, Image , Image , unsubstituted loweralkyl, or substituted loweralkyl having one to three substituents each of which being independently cyano, hydroxy, cyclo- hexyl, furyl, thienyl, Image , Image , Image , Image , Image or Image , k being 1, 2 or 3, W being each independently hydrogen, halogen, hydroxy, loweralkyl, trifluoromethyl, lower- alkoxy, nitro, amino, diloweralkylamino, phenoxy, or ben- zyloxy, and Z being hydrogen, loweralkyl or halogen, which are useful as antipsychotic and analgesic agents; novel intermediate compounds therefor; and methods of syn- thesizing the foregoing compounds.
467151
Davis Larry
Effland Richard C.
Kapples Kevin J.
Bereskin & Parr
Davis Larry
Effland Richard C.
Hoechst-Roussel Pharmaceuticals Inc.
Kapples Kevin J.
LandOfFree
11-substituted 5h,11h-pyrrolo¬2,1-c|¬1, 4|benzoxazepines, a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 11-substituted 5h,11h-pyrrolo¬2,1-c|¬1, 4|benzoxazepines, a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 11-substituted 5h,11h-pyrrolo¬2,1-c|¬1, 4|benzoxazepines, a... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1310543