11beta-hsd1 active compounds

Details 11beta-hsd1 active compounds 11beta-hsd1 active compounds

C - Chemistry, Metallurgy

07

D

C07D 451/06 (2006.01) A61K 31/166 (2006.01) A61K 31/343 (2006.01) A61K 31/403 (2006.01) A61K 31/439 (2006.01) A61K 31/46 (2006.01) A61K 31/55 (2006.01) A61P 3/00 (2006.01) C07C 233/75 (2006.01) C07D 209/88 (2006.01) C07D 307/91 (2006.01) C07D 471/08 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2681934

A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11.beta. -hydroxysteroid dehydrogenase type 1 (11.beta.HSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.

L'invention concerne une classe novatrice de composés représentés par la formule générale (I), leur utilisation en thérapie, des compositions pharmaceutiques comprenant les composés, ainsi que leur utilisation dans la fabrication de médicaments. Les présents composés modulent l'activité de l'hydroxystéroïde déshydrogénase 11b de type 1 (11bHSD1) et sont donc utiles dans le traitement des maladies dans lesquelles une modulation est bénéfique, par exemple, le syndrome métabolique.

Affiliated with

Also associated with

Rating

11beta-hsd1 active compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 11beta-hsd1 active compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 11beta-hsd1 active compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1742807