12-25-kda bacterial proteins and their 116-58 kda polymers...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 39/04 (2006.01) A61K 39/102 (2006.01) C07K 1/00 (2006.01) C07K 1/04 (2006.01) C07K 1/16 (2006.01) C07K 14/195 (2006.01) C07K 14/21 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2351524

The present invention relates to bacterial proteins, particularly bacterial glycoprotein polymers with a molecular weight of 116 to 158kDa which exhibit unique immunogenic and biological activities and may be used in vaccines and in pharmaceutical compositions, e.g. for treating tumours, and as biological effectors, such as anti-proliferation agents and nucleases.

Cette invention a trait à des protéines bactériennes, notamment à des polymères de glycoprotéine bactérienne, d'un poids moléculaire de 116 à 158 kDa, faisant montre d'activités immunogènes et biologiques uniques et pouvant être utilisés dans des vaccins et des compositions pharmaceutiques, par exemple pour traiter des tumeurs, et comme effecteurs biologiques, notamment en tant qu'agents anti-prolifération et en tant que nucléases.

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