C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/231, 260/272
C07D 455/00 (2006.01) A61K 31/44 (2006.01) C07D 471/14 (2006.01)
Patent
CA 1300146
12b-Substituted 1-hydroxymethyl-octahydroindolo[2,3-a]- quinolizine derivatives, process for the preparation and pharmaceutical compositions containing them A b s t r a c t The invention relates to new racemic and optically active 12b-substituted 1-hydroxymethyl-octahydroindolo- [2,3-a]quinolizine derivatives of the formula (I) Image (I) wherein R1 and R2 are the same or different and represent hydrogen, halogen, nitro, amino, hydroxyl, alkyl having from 1 to 6 carbon atoms or alkoxy having from 1 to 6 carbon atoms; R3 and R5 are the same or different and represent hydrogen, alkyl having from 1 to 6 carbon atoms or aralkyl having from 1 to 6 carbon atoms in the alkyl moiety; R4 is alkyl having from 1 to 6 carbon atoms, aryl or aralkyl having from 1 to 6 carbon atoms in the alkyl moiety; - 2 - R6 is hydrogen or alkyl having from 1 to 6 carbon atomo, aryl or aralkyl having from 1 to 6 carbon atoms in the alkyl moiety, and isomere and acid additions salts thereof. The compounds of the invention are partly valuable intermediates, partly are pharmaceutically active themselves.
507054
Balogh Zsuzsanna Nee Kardos
Csomor Katalin
Forgacs Lilla
Incze Maria
Karpati Egon
Balogh Zsuzsanna Nee Kardos
Csomor Katalin
Fetherstonhaugh & Co.
Forgacs Lilla
Incze Maria
LandOfFree
12b-substituted 1-hydroxymethyl-octahydroindolo¬2,3-a|-... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 12b-substituted 1-hydroxymethyl-octahydroindolo¬2,3-a|-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 12b-substituted 1-hydroxymethyl-octahydroindolo¬2,3-a|-... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1231315