13-cis prostaglandin derivatives and methods of making

Details 13-cis prostaglandin derivatives and methods of making 13-cis prostaglandin derivatives and methods of making

C - Chemistry, Metallurgy

12

P

260/235.05

C12P 31/00 (2006.01) C07C 405/00 (2006.01) C07D 309/12 (2006.01) C12N 9/20 (2006.01)

Patent

CA 1038378

ABSTRACT 13-Cis prostaglandin derivatives; cis-octenol ether copper (I) lithium reagents and methods of making such reagents and using the reagents to prepare the 13-cis prostaglandin derivatives. The 13-cis prostaglandin derivatives exhibit prosta- glandin-like pharmacological properties and are further useful as intermediates for the corres- ponding prostaglandin isomers having the normal 13-trans configuration.

172898

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