13-methyl-erythromycin derivatives

Details 13-methyl-erythromycin derivatives 13-methyl-erythromycin derivatives

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01) A61P 33/02 (2006.01)

Patent

CA 2373117

The invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3, R4, R5, R17, R f, A, X, and Y are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula (1), methods of using the compounds of formula (1) in the treatment of infectictions and methods of preparing the compounds of formula (1).

L'invention concerne des composés de la formule (1) et des sels pharmaceutiquement acceptables, des promédicaments et des solvats desdits composés. Dans ladite formule, R<1>, R<2>, R<3>, R<4>, R<5>, R<17>, R<f>, A, X, et Y sont tels que définis dans le mémorandum descriptif. L'invention concerne en outre des compositions pharmaceutiques contenant les composés de la formule (1), des méthodes d'utilisation des composés de la formule (1) pour traiter des infections, et des méthodes de préparation des composés de la formule (1).

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