C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 53/00 (2006.01) A61K 31/565 (2006.01)
Patent
CA 2390226
The disclosed invention relates to the unexpected finding of novel steroids which are characterized by a 14.beta.,15.beta.-cyclopropane ring and a 17.alpha. hydroxymethyl group. These steroids according to the invention are found to have in common an androgenic activity. They can be used for the preparation of an agent for male contraception, as well as for the preparation of a medicament for the treatment of androgen insufficiency.
Cette invention a trait à la découverte inattendue de nouveaux stéroïdes se caractérisant par la présence d'un noyau cyclopropane-14.beta., 15.beta. et celle d'un groupe hydroxyméthyle-17.beta.. Ces stéroïdes, qui font montre d'une activité androgène, peuvent être utilisés comme agent contraceptif masculin ainsi que dans le cadre de la préparation d'un médicament traitant une carence en androgène.
Buma Bursi Roberta
de Gooyer Marcel Evert
Leysen Dirk
Louw Jaap Van Der
Akzo Nobel N.v.
Fetherstonhaugh & Co.
N.v. Organon
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