14.beta.-hydroxy 3-deoxycardenolides

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 31/00 (2006.01) C07J 11/00 (2006.01) C07J 13/00 (2006.01) C07J 17/00 (2006.01) C07J 19/00 (2006.01) C07J 41/00 (2006.01) C07J 53/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1090330

ABSTRACT OF THE DISCLOSURE There are disclosed processes for the preparation of 14.beta.-hydroxy 3-deoxycardenolides by oxidizing a 3.beta.,14.beta.- dihydroxy cardenolide to form a 3-oxo-14.beta.-hydroxy cardenolide, and subsequently direct deoxygenating the 3-keto group. There are also disclosed novel compounds from such processes which compounds have pharmaceutical activity.

251508

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