14-chlorodaumonycin and process for the preparation of...

C - Chemistry – Metallurgy – 07 – H

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260/208.1

C07H 15/252 (2006.01)

Patent

CA 1335199

(2"R)-14-Chloro-4'-O-tetrahydropyranyladriamycin of formula: Image (XI) Also methods of preparing (2"R)-4'-O-tetrahydropyranyla- driamycin of formula: Image (A) from 14-chlorodaunomycin of formula: from 14-chlorodaunomycin of formula: Image (I) The present compounds have pharmaceutical uses as antitumor agents.

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