14-membered macrolides derived from leucomycins

Details 14-membered macrolides derived from leucomycins 14-membered macrolides derived from leucomycins

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2432886

Novel 14-Membered Macrolides derived from Leucomycins comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and processes for the preparation of such compounds.

L'invention concerne des nouveaux macrolides à 14 éléments issus de leucomycines et comprenant une dose thérapeutiquement efficace d'un composé de l'invention en combinaison avec un support pharmaceutiquement acceptable. L'invention concerne également une méthode de traitement d'infections bactériennes par administration à un mammifère d'une composition pharmaceutique contenant une dose thérapeutiquement efficace d'un composé de l'invention, ainsi que des procédés de préparation de ces composés.

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