15-ethynyl-prostaglandin e2 and related compounds

Details 15-ethynyl-prostaglandin e2 and related compounds 15-ethynyl-prostaglandin e2 and related compounds

C - Chemistry, Metallurgy

07

C

260/235.01

C07C 405/00 (2006.01)

Patent

CA 1062705

ABSTRACT OF THE DISCLOSURE 7-(2.beta.-[(3S)-3-Ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.- hydroxy-5-oxo-1.alpha.-cyclo-pentyl)-cis-5-heptenoic acid, 2.beta.-[(3S)-3- ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.-hydroxy-5-oxo-1.alpha.-cyclopen- tane heptanoic acid, related compounds, and intermediates thereto are disclosed. The final products have activity as bronchodila- tors and in reducing gastric secretion.

250148

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