15-oxygenated sterol compounds and the use of such compounds...

A - Human Necessities – 61 – K

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A61K 31/575 (2006.01) C07J 9/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 1123739

UNITED STATES PATENT APPLICATION of GEORGE J. SCHROEPFER, JR., EDWARD J. PARISH, AND ANDREW A. KANDUTSCH for 15-OXYGENATED STEROL COMPOUNDS AND THE USE OF SUCH COMPOUNDS TO INHIBIT THE BIOSYNTHESIS OF MEVALONIC ACID ABSTRACT OF DISCLOSURE 15-oxygenated sterols, having the ability to inhibit the biosynthesis of mevalonic acid, and produce other effects derived from their ability to inhibit the biosynthesis of mevalonic acid, are disclosed. The 15-oxygenated sterols correspond to the structural formula:

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