17,18-dehydro-apovincaminol-3',4',5'- trimethoxybenzoate,...

C - Chemistry – Metallurgy – 07 – D

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C07D 461/00 (2006.01)

Patent

CA 1202029

Abstract The invention relates to the new 17,18- -dehydro-apovincaminol-3',4',5'-trimethoxy-benzoate of formula (1) (1) Image and acid addition salts thereof. According to another aspect of the invention there is provided a process for the preparation of these new compounds. Still another aspect of the invention is a pharmaceutical composition for treating skin disease accompanied by a patogenic cell proliferation, in particular psoriasis, which comprises a pharmaceutically affective amount of the new compound of formula (1) or a pharmaceutically acceptable acid addition salt thereof.

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