17-18-dehydro-apovincaminol and process therefor

Details 17-18-dehydro-apovincaminol and process therefor 17-18-dehydro-apovincaminol and process therefor

C - Chemistry, Metallurgy

07

D

260/272

C07D 461/00 (2006.01)

Patent

CA 1215061

ABSTRACT OF DISCLOSURE The invention relates to a process for preparing a compound of formula (II) Image (II) or an acid addition salt thereof which comprises reducing a compound of formula (III) Image (III) with a selective reducing agent, and where required, forming an acid addition salt of the compound of formula (II) so obtained, and to compounds of formula II. The compounds of formula II are useful as intermediates in the preparation of 17, 18-dehydro-apovincaminol-3',4',5'-trimethoxy-benzoate of formula(I) Image (I) for treating skin disease for example psoriasis.

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