17.alpha.-acyloxy-5.beta. and 5.alpha. corticoids

Details 17.alpha.-acyloxy-5.beta. and 5.alpha. corticoids 17.alpha.-acyloxy-5.beta. and 5.alpha. corticoids

C - Chemistry, Metallurgy

07

J

260/63, 260/81

C07J 5/00 (2006.01) C07J 7/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 51/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1155108

ABSTRACT OF THE DISCLOSURE 17.alpha.1-Acy1oxy-5.beta.-pregnanes (I) and 17.alpha.-acyloxy-5.alpha.-pregnanes (IV) have an excellent activity split providing high topical anti- inflammatory activity with very low systemic side effects.

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