17.alpha. fluoroalkyl steroids, method for producing the...

Details 17.alpha. fluoroalkyl steroids, method for producing the... 17.alpha. fluoroalkyl steroids, method for producing the...

C - Chemistry, Metallurgy

07

J

C07J 73/00 (2006.01) A61K 31/565 (2006.01) A61P 5/26 (2006.01) C07J 1/00 (2006.01) C07J 11/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2422056

The invention relates to 17.alpha. fluoroalkyl steroids of the general formula (I), STEROID (I), wherein R3 represents a group of the formula CnFmHo, wherein n = 1, 2, 3, 4, 5 or 6, m > 1 and m+o = 2n+1. The invention further relates to methods for producing the same and to compositions that contain said compounds. The inventive composition of the general formula (I) possess androgenic activity.

L'invention concerne des 17.alpha.-fluoralkylstéroïdes de formule générale (I) STEROIDE (I), dans laquelle R¿3? signifie un reste de formule CnFmHo, où n = 1, 2, 3, 4, 5 ou 6, m > 1 et m+o = 2n+1. La présente invention porte également sur leur procédé de production et sur des compositions pharmaceutiques contenant ces composés. Selon l'invention, les composés de formule générale (I) ont une activité androgène.

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