17.alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified...

C - Chemistry – Metallurgy – 07 – J

Patent

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260/18, 167/194,

C07J 1/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 1327791

ABSTRACT OF THE DISCLOSURE Steroids of the formula: Image (II) Image Image (.DELTA.'OPTIONAL) (III) (IV) which are characterized by a 17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or ethynylmethyl substituent and a 17.beta.-hydroxy/- esterified hydroxy substituent. The steroids of this invention have glucocorticoid, anti-glucocorticoid, progestational, or anti-progestational activity, depending on the particular structure.

547105

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