C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 73/00 (2006.01) A61K 31/58 (2006.01) A61K 31/675 (2006.01)
Patent
CA 2135057
2135057 9323038 PCTABS00028 Novel amino substituted 4-azasteroid 5.alpha.-reductase inhibitors of formula (I), wherein A is (a), (b) or (c), are claimed as well as pharmaceutically acceptable salts and formulations thereof. These compounds are effective in inhibiting testosterone 5.alpha.-reductase(s) and are thus useful in the treatment of a number of hyperandrogenic conditions including benign prostatic hypertrophy, acne, seborrhea, female hirsutism, and male and female pattern baldness (alopecia).
Bergman Jeffrey P.
Tolman Richard L.
Witzel Bruce E.
Merck & Co. Inc.
Swabey Ogilvy Renault
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