17.beta.-aryl-4-aza-steroid derivatives

Details 17.beta.-aryl-4-aza-steroid derivatives 17.beta.-aryl-4-aza-steroid derivatives

C - Chemistry, Metallurgy

07

J

C07J 73/00 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2188034

Compounds of formula (T) are inhibitors of 5a-reductase and are useful alone or in combination with other active agents for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.

La présente invention concerne des composés représentés par la formule générale (I). Ces composés, qui sont des inhibiteurs de la 5.alpha.-réductase, s'utilisent seuls ou en combinaison avec d'autres principes actifs pour traiter les troubles associés à l'hyperandrogénie tels que l'acné vulgaire, la séborrhée, l'hirsutisme, l'alopécie androgénétique et l'hyperplasie bénigne de la prostate.

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