17.beta.- hydroxy-.delta..sup.4- androsten-3-ones and...

C - Chemistry – Metallurgy – 07 – J

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C07J 9/00 (2006.01) C07J 1/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1105004

ABSTRACT OF THE DISCLOSURE The present invention provides 17.beta.-hydroxy-.DELTA.4-androsten- 3-ones of the formula I Image (I) in which R2 represents a hydrogen atom or an organic acid acyl group, R3 represents a methyl or ethyl group, R4 represents a hydrogen atom or a methyl group, Image represents a Image grouping, a Image grouping, the -CH2- group being in the 6.alpha.,7.alpha.- or 6.beta.,7.beta.-position, or a Image grouping, R1 representing a lower alkyl group, and Image represents a Image grouping or a Image grouping, the -CH2- group being in the 15.alpha., 16.alpha.- or 15.beta.,16.beta.-position which are useful as diuretics of the type of aldosterone-antagonists.

303341

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