C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
167/198, 260/28.
C07J 31/00 (2006.01) A61K 31/565 (2006.01)
Patent
CA 1245215
ABSTRACT 17.beta.-(SUBSTITUTED THIO)ANDROSTENES Antiinflammatory activity is exhibited by new steroids having the formula Image or the 1,2-dehydro derivative thereof, wherein R1 is alkyl, alkanoyloxyalkyl, arylcarbonyloxy- alkyl, alkenyl, alkynyl, cycloalkyl, aryl or arylalkyl; R2 is hydrogen, hydroxy, alkoxy, aryloxy, methylene, alkylthio, arylthio, alkanoyl, alkanoyloxy, or halogen; R3 is hydrogen, methyl, hydroxy or halogen; and n is 0, 1 or 2.
480870
Haugwitz Rudiger D.
Varma Ravi K.
Osler Hoskin & Harcourt Llp
Squibb (e.r.) & Sons Inc.
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