C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 43/00 (2006.01) A61K 31/57 (2006.01) A61K 31/585 (2006.01) C07J 5/00 (2006.01)
Patent
CA 2512987
The present invention encompasses compounds of Formula (I) or ph armaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharamaceutical compositions and methods of use are also included.
La présente invention se rapporte à des composés représentés par la formule (I) ou à des sels ou hydrates pharmaceutiquement acceptables de ces composés, qui s'avèrent utiles en tant que ligands des récepteurs aux glucocorticoïdes permettant de traiter diverses maladies ou affections auto-immunes et inflammatoires. L'invention se rapporte également à des compositions pharmaceutiques et à des procédés d'utilisation associés.
Ali Amjad
Balkovec James M.
Graham Donald W.
Greenlee Mark L.
Taylor Gayle E.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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