17-halomethylene estratrienes

Details 17-halomethylene estratrienes 17-halomethylene estratrienes

C - Chemistry, Metallurgy

07

J

167/193, 260/57

C07J 13/00 (2006.01) A61K 31/56 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1324374

Abstract of the Disclosure Novel 17-halomethylene estratrienes of Formula I Image (I), wherein R1 is hydrogen, a methyl or acyl group, and R2 is a halogen atom, show low affinity to the estrogen receptor and bring about a cellular membrane and blood/lymphatic vessel permeability that is increased as compared with estradiol.

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