17-spiromethylene steroids

Details 17-spiromethylene steroids 17-spiromethylene steroids

C - Chemistry, Metallurgy

07

J

C07J 21/00 (2006.01) A61K 31/58 (2006.01) C07J 31/00 (2006.01) C07J 33/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01) C07J 53/00 (2006.01) C07J 63/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2100514

The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: <See formula I> wherein R a and R b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.

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