17alfa, 21-dihydroxypregnene esters as antiandrogenic agents

Details 17alfa, 21-dihydroxypregnene esters as antiandrogenic agents 17alfa, 21-dihydroxypregnene esters as antiandrogenic agents

C - Chemistry, Metallurgy

07

J

C07J 5/00 (2006.01) A61K 31/573 (2006.01) A61P 5/28 (2006.01) A61P 15/16 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2454675

17.alpha.,21-Dihydroxypregna-4,9-diene-3,20-dione and 17.alpha.,21- dihydroxypregna-4-ene-3,20-dione 17 and/or 21 esters of having remarkable antiandrogenic activity, and the processes for the preparation thereof.

L'invention concerne des esters 17 et/ou 21 de 17.alpha.,21-dihydroxyprégna-4,9-diène-3,20-dione et de 7.alpha.,21-dihydroxyprégna-4-ène-3,20-dione possédant une activité anti-androgène remarquable, et leurs procédés de préparation.

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