C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 43/00 (2006.01) A61K 31/565 (2006.01) A61K 31/567 (2006.01) A61K 31/58 (2006.01) A61P 5/28 (2006.01) C07J 41/00 (2006.01) C07J 63/00 (2006.01)
Patent
CA 2683522
Compounds having the structure, their salts or N-oxide derivatives: are used to treat or reduce le likelihood of acquiring androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and male baldness. They can be formulated together with pharmaceutically acceptable diluent or carrier or otherwise made into any pharmaceutical dosage form. Combinations with other active pharmaceutical agents are also disclosed.
L'invention concerne des composés ayant la structure (I), leurs sels ou des dérivés de N-oxyde utilisés pour traiter ou réduire la probabilité de contracter des maladies dépendantes des androgènes telles que le cancer de la prostate, l'hyperplasie prostatique bénigne, le syndrome ovarien polykystique, l'acné, l'hirsutisme, les états séborrhéiques, l'alopécie androgénique et la calvitie masculine. Ces composés peuvent être formulés avec un diluant ou un excipient pharmaceutiquement acceptable ou produits d'une autre façon sous forme pharmaceutique. L'invention concerne également des combinaisons avec d'autres agents pharmaceutiques actifs.
Cloutier Julie
Dion Sylvain
Gauthier Sylvain
Labrie Fernand
Mailhot Josee
Endorecherche Inc.
Marks & Clerk
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