C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
167/192, 260/38,
C07J 41/00 (2006.01) A61K 31/565 (2006.01) C07J 43/00 (2006.01)
Patent
CA 1284318
ABSTRACT A novel class of steroids having pregnancy-terminating and/or pregnancy-preventing activity and a very low antigluccorticoid activity have been found. The compounds have the general formula: Image wherein R1 and R2 each separately represent H or a (1-4 C) hydrocarbon radical or together represent a (2-6 C) hydrocarbon radical, R3 represents H or a (1-4 C) hydrocarbon radical, optionally having an OH substituent, R4 represents OH or an ester or ether group, or together with R3 represents O or a heterocyclic ring system containing O, and wherein the broken line indicates an optionally present double bond between the carbon atoms at positions 9 and 10 of the steroid skeleton. Processes for their preparation and pharmaceutical compositions comprising these compounds as pharmaceutically active substances also comprise further aspects of the invention.
541648
de Jongh Hendrik P.
Heuvel Martinus J. Van Den
Akzo N.v.
de Jongh Hendrik P.
Fetherstonhaugh & Co.
Heuvel Martinus J. Van Den
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