19-fluoro- or cyano- 21-hydroxyprogesterone derivatives...

Details 19-fluoro- or cyano- 21-hydroxyprogesterone derivatives... 19-fluoro- or cyano- 21-hydroxyprogesterone derivatives...

C - Chemistry, Metallurgy

07

J

167/191, 260/64

C07J 5/00 (2006.01) A61K 31/57 (2006.01) C07J 13/00 (2006.01) C07J 21/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1321579

ABSTRACT OF THE DISCLOSURE 19-Fluoro- and cyano- substituted 21-hydroxyprogesterone derivatives and related compounds which are active as 19- hydroxylase inhibitors and useful as antihypertensive agents are described herein. The compounds are prepared using appropriate synthetic pathways which will vary according to the nature of the specific 19-substituted progesterone or related compound desired. M01324

604022

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