(1h-azol-1-ylmethyl) substituted quinoline, quinazoline or...

Details (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or... (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or...

C - Chemistry, Metallurgy

07

D

167/211, 260/253

C07D 401/00 (2006.01) C07D 403/06 (2006.01) C07D 409/14 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2002864

(1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives, compositions containing the same, and methods of treating mammals suffering from disorders which are characterized by an excessive proliferation and/or abnormal differentiation of epithelial tissues. Process for preparing (1H-azol-1- ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives having the general formula I: (see formula I) wherein -X1=X2- is a bivalent radical, R is H or lower alkyl, Y is H or an alkyl, cycloalkyl, aromatic, substituted aromatic, alkenyl or alkynyl group, and Z is a quinoline, quinazoline or quinoxaline derivative.

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