C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) C07D 231/54 (2006.01) C07D 231/56 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2481320
The present invention encompasses compounds of Formula I: (I) or pharmaceutically acceptable salts or hydrates thereof, which are useful as selective glucocorticoid receptor ligands for treating a variety of autoimmune and inflammatory diseases or conditions. Pharamaceutical compositions and methods of use are also included.
L'invention concerne des composés de formule I, ou des sels pharmaceutiquement acceptables ou des hydrates de ceux-ci, utilisés en tant que ligands sélectifs du récepteur glucocorticoïde, dans le traitement de diverses maladies ou affections auto-immunes et inflammatoires. L'invention concerne également des compositions pharmaceutiques et des méthodes d'utilisation associées.
Ali Amjad
Balkovec James M.
Graham Donald W.
Quraishi Nazia
Thompson Christopher F.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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