1h-imidazo¬4,5-d|pyridazin-7-ones,...

Details 1h-imidazo¬4,5-d|pyridazin-7-ones,... 1h-imidazo¬4,5-d|pyridazin-7-ones,...

C - Chemistry, Metallurgy

07

D

C07D 471/02 (2006.01) A61K 31/4188 (2006.01) A61P 25/00 (2006.01) C07D 471/04 (2006.01) C07D 487/02 (2006.01)

Patent

CA 2351724

Corticotropin releasing factor (CRF) antagonists of formula (I), and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress.

La présente invention, qui concerne des antagonistes de la corticolibérine représentés par la formule générale (I), concerne également leur utilisation pour le traitement, d'une part des états anxieux et dépressifs et d'autres troubles psychiatriques et neurologiques, d'autre part d'affections immunologiques, cardio-vasculaires ou à implication cardiaque, et enfin de l'hypersensibilité colique liée à des troubles psychopathologiques et au stress.

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