1h-imidazole derivatives and process for their production

Details 1h-imidazole derivatives and process for their production 1h-imidazole derivatives and process for their production

C - Chemistry, Metallurgy

07

D

260/305

C07D 409/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1250586

ABSTRACT OF THE DISCLOSURE: The present invention relates to 1H-imidazole derivatives of the general formula (I): Image (I) wherein [A] is an imino- Image or methyne- Image group, R1 and R2 are both hydrogen or halogen, or R1 and R2 are either hydrogen or halogen respectively, being the halogen selected from chlorine, bromine or fluorine in either of the 2, 4, 5, 6 or 7 positions of the benzo[b]thiophene group, and the methylene (-CH2-) group is bonded to the benzo[b]thiophene group in its 2 or 3 position, and the non-toxic addition salts, preferably the mononitrates and the heminaphthalen- 1,5-disulphonates, as well as to a process for preparing these compounds and to pharmaceutical compositions containing these compounds. The above compounds are useful for combat- ing fungi and yeast infections.

472063

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