[ (1h- indol- 5 -yl) -heteroaryloxy] - (1-aza-bicyclo...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) A61K 31/439 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2631654

The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I) wherein the substituents are as defined in the specification and to processes for their production to pharmaceutical compositions comprising them and to their use in the manufacture of a medicament for the treatment and/ or delay of progression of psychotic and nemodegenerative disorders.

La présente invention concerne des dérivés de 1-aza-bicycloalkyle répondant à la formule (I) dans laquelle les substituants sont tels que définis dans la description. L~invention concerne également des procédés permettant leur production, des compositions pharmaceutiques les comprenant ainsi que leur utilisation pour la fabrication d~un médicament destiné à traiter et/ ou à retarder la progression de troubles psychotiques et neurodégénératifs.

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