1h-indole-3-acetamide spla2 inhibitors

Details 1h-indole-3-acetamide spla2 inhibitors 1h-indole-3-acetamide spla2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/04 (2006.01) A61K 31/405 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/675 (2006.01) C07D 209/22 (2006.01) C07D 209/24 (2006.01) C07D 209/30 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 403/02 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 417/02 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2121323

Abstract A class of novel 1H-indole-3-acetamides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

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