1h-pyrazolyl derivative compounds, for use in diseases...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61P 25/00 (2006.01) C07D 231/14 (2006.01) C07D 231/16 (2006.01) C07D 231/18 (2006.01) C07D 231/38 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2471880

Disclosed are pyrazolyl derivative compounds or purified stereoisomers or stereoisomer mixtures of said compounds and their salts or prodrug forms thereof which have structural formula (I) or (II): wherein the variables R, R1, R2, R5 and R6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT2C receptor .

La présente invention se rapporte à des composés dérivés de pyrazolyle, à des stéréoisomères purifiés ou à des mélanges de stéréoisomères de ces composés, à leurs sels ou à leurs formes de promédicaments. Ces composés présentent les formules structurelles (I) et (II), dans lesquelles les variables R, R¿1?, R¿2?, R¿5? et R¿6? sont définies dans les spécifications. Ces composés s'avèrent utiles pour le traitement ou la prévention des maladies et/ou des comportements impliquant le récepteur 5-HT¿2C?.

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