1h-tetrazole-5-carboxamide derivatives

Details 1h-tetrazole-5-carboxamide derivatives 1h-tetrazole-5-carboxamide derivatives

C - Chemistry, Metallurgy

07

D

260/312

C07D 257/04 (2006.01) C07C 205/37 (2006.01)

Patent

CA 1228857

NOVEL lH-TETRAZOLE -5- CARBOXAMIDE DERIVATIVES ABSTRACT OF THE INVENTION There are described compounds of the formula Image (I) in which R1 is hydrogen or C1-6 alkyl, R2 is hydrogen, C1-6 alkyl or C3-6 alkenyl, R3 is hydrogen or C1-6 alkyl, R4 is hydrogen or an N-protecting group, n is 2, 3, 4 or 5, and X is oxygen, sulphur or -CH2-, provided that when X is -CH2- n is O; and salts thereof. The compounds in which R4 is hydrogen have pharmaceutical activity.

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