1h-tretrazole derivatives

Details 1h-tretrazole derivatives 1h-tretrazole derivatives

C - Chemistry, Metallurgy

07

D

260/273

C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 1046064

ABSTRACT OF THE DISCLOSURE 1H-Tetrazole derivatives of the formula: Image and pharmaceutically acceptable salts thereof, wherein the ring P is pyridine ring; A is carbonyl, methylene or C2-4 alkylidene; Y is oxygen, sulfur or -N(R1)- wherein R1 is hydrogen or C1-4 alkyl; each of X1 and X2 is hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, phenyl or substituted phenyl, any substituent on the phenyl being halogen, C1-4 alkyl, C1-4 alkoxy or trifluoro- methyl; and T is hydrogen, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, hydroxy-C1-4 alkyl, C1-4 alkoxy-C1-4 alkyl, carboxy- C1-4 alkyl, C1-4 alkoxycarbonyl-C1-4 alkyl or substituted or unsubstituted amino-C1-4 alkyl, any substityted amino being C1-4 alkyl- or di-C1-4 alkyl-amino, piperidino, 1-pyrrolidinyl, morpholino, 1-piperazinyl and 4-C1-4 alkyl-1-piperazinyl; are useful as anti-allergic agents.

227467

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