(1r,1'r)-atracurium salts separation process

C - Chemistry – Metallurgy – 07 – D

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C07D 217/20 (2006.01) C07B 57/00 (2006.01)

Patent

CA 2687157

The present invention provides an improved method for obtaining cisatracurium besylate, which preferably includes chromatographically separating cisatracurium besylate from a mixture of (1R,1'R)-atracurium isomers via flash chromatography

La présente invention porte sur un procédé amélioré permettant d'obtenir du bésylate de cisatracurium, qui consiste, de préférence, à séparer par voie chromatographique le bésylate de cisatracurium d'un mélange d'isomères de (1R,1'R)-atracurium par chromatographie éclaire.

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