(1r,5s,6s)-2-substituted...

Details (1r,5s,6s)-2-substituted... (1r,5s,6s)-2-substituted...

C - Chemistry, Metallurgy

07

D

167/233, 260/299

C07D 477/20 (2006.01) A61K 31/415 (2006.01) C07D 519/00 (2006.01) C07D 519/06 (2006.01)

Patent

CA 1340274

Novel carbapenem compounds (1R,5S,6S)-2-substituted thio-6-[(R)-1-hydroxyethyl]-1-methyl-carbapenem-3-carboxylic acid derivatives are disclosed. These carbapenem compounds are represented by the following formula: (see fig. I) and have a beta-coordinated methyl group introduced into the 1-position and a 4-pyrazolizinylthio group or a 6,7-dihydro-5H- pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio group introduced into the 2-position. In the formula, R1 represents a radical of the formula: (see fig. II) or (see fig. III) and R2 is a hydrogen atom or an anion charge. They have antibacterial activity, and are used for prevention and treatment of bacterial infections as antibacterial agents. A process for producing these carbapenem compounds is also disclosed.

563607

Affiliated with

Also associated with

Rating

(1r,5s,6s)-2-substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with (1r,5s,6s)-2-substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (1r,5s,6s)-2-substituted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1261264