2-(1,3-diazacycloalkenyl)-2-hydrazones of substituted chalcones

Details 2-(1,3-diazacycloalkenyl)-2-hydrazones of substituted chalcones 2-(1,3-diazacycloalkenyl)-2-hydrazones of substituted chalcones

C - Chemistry, Metallurgy

07

D

260/381.1

C07D 243/04 (2006.01) C07D 233/06 (2006.01) C07D 233/52 (2006.01) C07D 239/18 (2006.01)

Patent

CA 1044243

ABSTRACT A substituted chalcone of the formula: Image ?HX wherein R1 and R2 are the same or different and are mono- halophenyl, dihalophenyl, monomethylphenyl, dimethylphenyl, trimethylphenyl, tetramethylphenyl, monoalkoxy C1-C4 phenyl, dialkoxy C2-C8 phenyl, C1-C4-alkylthiophenyl, methylsulfonyl- phenyl, trifluoromethylphenyl, anthryl, naphthyl or biphenyl- yl; R is hydrogen, methyl or chlorophenyl; Z is Image - wherein n is 2, 3 or 4 and X is chloro, iodo or bromo, and a process for the preparation of said compounds which comprises heating a compound of the formula: Image ?HX wherein Z and X are as defined above, with a compound of the formula: Image wherein R, R1 and R2 are as defined in the presence of a hydrophilic solvent and a hydrohalic acid and recovering said compound therefrom.

217044

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