2-(1-piperidyl) ethanol derivatives, their preparation and...

Details 2-(1-piperidyl) ethanol derivatives, their preparation and... 2-(1-piperidyl) ethanol derivatives, their preparation and...

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/47 (2006.01) C07D 211/08 (2006.01)

Patent

CA 2072520

- 61 - ABSTRACT A compound which is a 2-(1-piperidyl)ethanol derivative of the general formula (I) Image (I) in which R1 represents hydrogen, halogen or methyl, R2 represents one or two substituents independently chosen from halogen, (C1-4)alkyl, hydroxyl, (C1-4)alkoxy, trifluoromethyl, acetylamino and methylsulphonylamino, and either X represents a CH2 group and Y represents a CH2, (CH2)2 or CO group, or X represents a CO group and Y represents a CH2 group, provided that R1 and R2 are not both hydrogen when X and Y each represent a CH2 group, or a pharmaceutically acceptable acid addition salt thereof; process for the preparation and the therapeutic application thereof. An intermediate useful for the synthesis of a 2-(1- piperidyl)ethanol derivative of formula (I) or a pharmaceutically acceptable acid addition salt thereof.

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