2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri

Details 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri

C - Chemistry, Metallurgy

07

D

C07D 209/30 (2006.01) A61K 31/404 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2551168

The present invention relates to aniline derivatives of the general formula I and their use as serotonin reuptake inhibitors and preferably also norepinephrine reuptake inhibitors in the treatment of depression, anxiety, affective disorders, pain disorders, attention deficit hyperactivity disorder (ADHD) and stress urinary incontinence.

La présente invention concerne des dérivés d'aniline représentés par la formule générale (I) et leur utilisation comme inhibiteurs spécifiques de la recapture de la sérotonine et de préférence également comme inhibiteurs de la recapture de la noradrénaline dans le traitement de la dépression, de l'anxiété, des troubles affectifs, de la douleur, du trouble de déficit de l'attention/de l'hyperactivité (TDA/H) et de l'incontinence urinaire d'effort.

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