2,2-difluoro-3-carbamoyl ribose sulfonate compounds and...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 19/073 (2006.01) C07D 307/33 (2006.01) C07H 11/00 (2006.01) C07H 13/12 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2167361

This invention provides novel 1-alkylsulfonyl--2,2-difluoro-3-carbamoyl ribose intermediates and intermediate nucleosides derived therefrom. The compounds are particularly useful in the preparation of 2'-deoxy--2',2'-difluoro-beta-cytidine and other beta anomer nucleosides which are antiviral and anticancer agents.

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