2,2-dimethylchromene derivatives, process for their...

Details 2,2-dimethylchromene derivatives, process for their... 2,2-dimethylchromene derivatives, process for their...

C - Chemistry, Metallurgy

07

D

167/231, 260/279

C07D 405/04 (2006.01) A61K 31/44 (2006.01) A61K 31/675 (2006.01) C07F 9/547 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 1329603

IN THE C A N A D I A N PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: 2,2-Dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present in the names of: Georges GARCIA Alain DI MALTA Patrick GAUTIER Assignee: SANOFI ABSTRACT The present invention relates to 2,2-dimethyl- chromene derivatives of the formula : (I) Image in which Z represents a halogen atom or a cyano, nitro, acetyl, phosphono or dialkoxyphosphoryl group, the alkoxy group containing 1 to 3 carbon atoms, and the pharmaceutically acceptable salts of the phosphono group. These compounds show an antihypertensive and antiarrythmic activity. The present invention also relates to a process for the preparation of said compounds and to the pharmaceutical compositions in which they are present.

579795

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