2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and...

Details 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and... 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and...

C - Chemistry, Metallurgy

07

C

167/179, 260/244

C07C 237/20 (2006.01) A61K 31/165 (2006.01) C07C 217/30 (2006.01) C07C 217/34 (2006.01) C07C 235/20 (2006.01) C07C 237/12 (2006.01) C07C 259/06 (2006.01) C07D 213/40 (2006.01) C07D 261/02 (2006.01) C07D 295/185 (2006.01)

Patent

CA 1326025

ABSTRACT OF THE DISCLOSURE 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds are disclosed, of general formula (I) Image (I) R1 is hydrogen, fluoro or chloro, possible values of R2 include hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl and phenyl and possible values of R3 include hydrogen, alkyl, hydroxy and alkoxy, or R2 and R3 together form a methylene chain. The compounds are useful in the treatment of obesity and related conditions. Processes for their preparation are described, as are novel intermediates and pharmaceutical compositions containing them.

588767

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