2-(2-picolylsulfur)-trienoimidazole derivatives

Details 2-(2-picolylsulfur)-trienoimidazole derivatives 2-(2-picolylsulfur)-trienoimidazole derivatives

C - Chemistry, Metallurgy

07

D

167/231, 260/277

C07D 495/04 (2006.01) A61K 31/44 (2006.01) C07D 495/14 (2006.01)

Patent

CA 1268461

Abstract of the disclosure: Substituted thienoimidazole derivatives, processes for their preparation,pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors. The invention relates to compounds of the formula I Image (I) in which A stands for (a) Image , (b) Image or (c) Image T denotes -S-, -SO- or -SO2-, R3 denotes hydrogen, alka- noyl, alkylcarbamoyl, alkoxycarbonyl, benzyloxycarbonyl or another physiologically tolerated protective group, R4 and R5 stand for hydrogen or alkyl, R6 and R8 denote hydrogen, halogen, alkyl or a substituent of the formula -O-[CH2]o-CpH(2p+1-q)Halq and R7 is hydrogen, (subst.)alkyl (subst.)alkoxy, -O-[CH2]o-CpH(2p+1-q)Halq, NR'R", alkyl- mercapto, alkylsulfinyl or alkylsulfonyl, a process for their preparation, pharmaceutical preparations containing these compounds and their use as medicaments.

574551

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