2-{[2-(substituted amino)ethyl]sulfonyl}ethyl...

Details 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl... 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl...

C - Chemistry, Metallurgy

07

F

C07F 9/24 (2006.01) A61K 31/664 (2006.01) A61K 31/675 (2006.01) A61P 35/04 (2006.01) C07F 9/572 (2006.01) C07F 9/59 (2006.01)

Patent

CA 2670628

2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N,N',N' -tetrakis(2-chloroethyl)-phosphorodiamidates, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies (I).

L'invention concerne des N,N,N',N'-tétracis(2-chloroéthyl)-phosphorodiamidates de 2-{[2-(amino substitué)éthyl]sulfonyl}éthyle, leur préparation et intermédiaires dans leur préparation, des compositions pharmaceutiques les contenant et des procédés de traitement les utilisant. Seuls et en combinaison avec d'autres thérapies anticancéreuses (I), lesdits composés sont utiles pour traiter le cancer.

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