2-(2-vinylpyrrolidinylthio)carbapenem derivatives

Details 2-(2-vinylpyrrolidinylthio)carbapenem derivatives 2-(2-vinylpyrrolidinylthio)carbapenem derivatives

C - Chemistry, Metallurgy

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C07D 477/00 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 477/20 (2006.01)

Patent

CA 2022681

A compound of the formula: Image (I) wherein R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or a lower alkyl group, each of R3, R4 and R5 is a hydrogen atom or a lower alkyl group, or R3 and R4 together form a methylene group, an ethylene group or a propylene group, or R4 and R5 form together with the adjacent nitrogen atom an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group or a morpholino group; or a pharmaceutically acceptable salt or ester thereof.

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